Reactive or Sensitive Skin: Understanding and Calming Cutaneous Reactions

Reading time : 4 min

Sudden redness, tingling, burning sensations…
Reactive skin responds to stimuli that are sometimes invisible: temperature changes, an unsuitable product, or even emotional stress.
Often confused with sensitive skin, reactive skin is a dermatological reality of its own. Understanding how it works is the first step to protecting and soothing it.

Sensitive, Reactive, or Allergic Skin: What’s the Difference?

These terms seem similar, yet they differ greatly in origin and management:

  • Sensitive skin is fragile or thin, often dry, and reacts easily to external aggressions (pollution, wind, irritants).
  • Reactive skin is defined by excessive nerve hyperreactivity: its sensory fibers send discomfort signals to the brain too quickly.
  • Allergic skin involves a specific immune reaction to an identified allergen.

In other words, reactive skin feels before it shows — it reacts even without visible signs.

Why Do Some Skin Types Become Reactive?

Reactive skin results from several biological mechanisms:

1. A disrupted skin barrier

The stratum corneum no longer acts as an effective shield, allowing irritants to penetrate and increasing water loss (TEWL).

2. Hyperexcitability of sensory nerve endings

Sensory receptors — particularly TRPV1 — become hypersensitive, amplifying every stimulus (heat, cold, emotional stress, cosmetics).

3. Silent inflammation

The skin releases pro-inflammatory neuromediators that maintain sensations of discomfort and warmth.

This explains why reactive skin needs skincare that targets both the skin barrier and the nervous response.

Best Practices to Soothe Reactive Skin

1. Cleanse Without Irritation

Reactive skin must be cleansed with an ultra-gentle base — without sulfated surfactants or fragrance.
High-tolerance cleansing creams are ideal: they preserve lipids and respect the microbiome.

Tip: Avoid hot water and pat the skin dry gently without rubbing.

2. Soothe and Deeply Hydrate

The priority is to rehydrate the skin and repair the barrier to reduce nerve signal transmission.

Choose skincare that is:

  • rich in biomimetic agents (squalane, ceramides, essential fatty acids)
  • formulated with soothing and neurocosmetic actives (CM-Glucan, Circalys, Centella asiatica)
  • free of alcohol, fragrance, essential oils, and silicones

These formulas help restore skin tolerance day after day.

3. Reduce External Triggers

Reactive skin is highly sensitive to temperature variations, pollution, and emotional stress.

Simple habits can reduce flare-ups:

  • protect skin from cold and wind
  • use SPF 50 all year
  • avoid mechanical exfoliation and frequent scrubs
  • practice slow breathing or calming routines to reduce stress

Neurocosmetics: A New Approach for Reactive Skin

Neurocosmetics explores the link between the nervous system and skin comfort.
Certain molecules — such as peptides or neuro-active plant extracts — regulate communication between cutaneous neurons and keratinocytes, helping the skin restore its tolerance threshold.

Thanks to biotechnology, this approach provides skincare that soothes reactive skin at the source, rather than simply masking symptoms.

Restoring Skin Tolerance

Reactive skin is not a fatality.
With scientifically formulated care, gentle hygiene, and daily attention, it is possible to “retrain” the skin to react less and live better.

At Skinalys, every formula reflects this belief: combining biotechnological innovation, dermatological transparency, and absolute respect for sensitive skin.

Scientific References
  1. Lévêque, J.-L. The perception of the skin: neurocosmetic implications. Int J Cosmet Sci (2012).
  2. Misery, L. et al. Sensitive skin in the European population. JEADV (2018).
  3. Proksch, E. et al. The skin barrier function. Clin Dermatol (2008).
  4. Voegeli, R. et al. Tolerance testing in sensitive skin. Cosmetics (2019).
  5. Saint-Martory, C. et al. Neurogenic inflammation and barrier dysfunction. Exp Dermatol (2019).
Scientific Note

Neurodermatological research highlights the key role of cutaneous sensory fibers in hypersensitivity reactions.
Studies on TRPV1 receptors (Lévêque, 2012) and transepidermal water loss (Proksch, 2008) confirm that reactivity is both neurological and dermatological.

High-tolerance biomimetic and neurocosmetic formulations now offer a scientifically validated pathway to restoring the stability of reactive skin.

The Range

SKINALYS® has developed a complete routine powered by plant-based biotechnology, where each product plays a complementary role in soothing, protecting and supporting the balance of sensitive and atopic-prone skin, with maximum tolerance and proven efficacy.

Powered by next-generation biomimetic and neurocutaneous actives, the SKINALYS® routine supports the skin’s natural repair processes while reinforcing elasticity and firmness for a visibly healthier complexion*.

*In vivo & in vitro clinical tests

Restore+ Serum

High-tolerance biotechnological serum – soothes, helps restore the skin barrier and supports the skin’s natural renewal

Barrieer+ Day Cream

Barrier-strengthening dermo-fortifying cream – hydrates, soothes and reinforces the skin barrier

DermActif Cleanser

Protective cleansing cream – soothes, hydrates and respects the skin microbiome