Clinically Proven Skin Benefits (in vivo & in vitro)

• Accelerated regeneration — shortens cellular renewal time and promotes skin repair.
• Soothing effect — reduces redness and inflammation following chemical
(detergent) or UV-induced irritation.
• Enhanced hydration — improves the skin’s ability to retain moisture,
reducing dryness and discomfort.
• Protective action — acts as an anti-inflammatory and antioxidant, helping to prevent imperfections (anti-acne effect).

Function within SKINALYS® Formulations

A soothing and repairing active, Allantoin quickly calms irritation, supports cell renewal, and protects sensitive skin day after day.

Clinically Proven Skin Benefits

• Maximum tolerance — non-irritating formula perfectly suited to sensitive and atopy-prone skin.
• Hydration preservation — prevents dryness even after repeated washing and helps maintain skin suppleness.
• Effective & sensory cleansing — produces a creamy, pleasant foam that leaves the skin feeling fresh and comfortable.
• Daily protection — respects the skin barrier and helps prevent tightness and discomfort.

Function within SKINALYS® Formulations

Amilite® GCS-12K serves as the intelligent cleansing base in our cleanser. t combines deep cleansing efficacy with the gentleness of skincare, ensuring clean, soothed, and comfortable skin — perfectly prepared to receive reparative actives.

Clinically Proven Skin Benefits (ex vivo & in vivo)

• Strengthens the protective flora — stimulates the growth of beneficial bacteria while limiting those responsible for irritation or imperfections.
• Activates natural defenses — increases the production of protective peptides, the skin’s natural “shields” (ex vivo tests).
• Rebalances the microbiome — quickly restores the skin’s flora after stress, pollution, repeated cleansing, or dermatological treatments.
• Improves skin resilience — enhances daily comfort and reduces imbalances responsible for redness and irritation (in vivo tests).

Function within SKINALYS® Formulations

As a key microbiome-protecting active, BioEcolia® helps preserve beneficial flora, stimulates natural defenses, and promotes skin that is stronger, more balanced, and visibly soothed.

Clinically Proven Skin Benefits (in vivo)

• Wrinkle reduction:
  −13 % after 2 weeks and −16 % after 4 weeks (crow’s feet)
  −38 % after 2 weeks and −46 % after 4 weeks (under-eye area)
• Improved elasticity: +32 % after 2 weeks and +47 % after 4 weeks
• Enhanced hydration: +83 % immediately and +64 % after 4 weeks

Function within SKINALYS® Formulations

A global rejuvenation active, Bio-Placenta reactivates the skin’s natural growth and repair processes, improves elasticity and hydration, and visibly reduces wrinkles and signs of fatigue.

Clinically Proven Skin Benefits (in vivo & in vitro)

• Immediate soothing: reduces redness by up to −81% after irritation (clinical test).
• Anti-inflammatory: limits inflammatory responses and visibly reduces skin irritation.
• Antioxidant: protects against free radicals and oxidative stress.
• Radiance & evenness: helps reduce hyperpigmentation and promotes a more uniform complexion.

Function within SKINALYS® Formulations

A benchmark soothing active, BisaboLife™ instantly calms irritation, reduces neurogenic inflammation, and protects sensitive and reactive skin from daily environmental stressors.

Proven Skin Benefits (in vivo)

• Firmness: +46% after 56 days
• Elasticity: +21% → equivalent to an estimated 14-year cellular rejuvenation
• Wrinkle reduction: –42.9% (crow’s feet)
• Overall improvement in complexion and skin texture:
  Wrinkles: –78%
  • Roughness: –51%
  Pores: –65%
  Dark spots: –30%
  Redness: –63%

Function within SKINALYS® Formulations

A key regenerative anti-aging active: it
counteracts signs of cellular fatigue linked to neurogenic inflammation and
helps restore a more even, radiant complexion.

Clinically Proven Skin Benefits (in vivo & in vitro)

• Strengthened skin barrier: limits transepidermal water loss and preserves hydration after external aggressions or dermatological procedures (laser, peeling).
  • Accelerated repair: promotes wound healing and quickly soothes weakened skin.
  • Neurocutaneous relief: reduces redness, itching, and sensations of discomfort.
  • Anti-aging protection: shields against UV-induced oxidative stress and visibly reduces wrinkle depth (−20% in 28 days).

Function within SKINALYS® Formulations

A defense-and-repair active par excellence, CM-Glucan helps the skin resist daily aggressions, accelerates recovery, and reduces visible signs of neurogenic inflammation.

Clinically Proven Skin Benefits (in vitro & in vivo)

• Strengthens natural defenses: stimulates the skin’s detoxifying and antioxidant enzymes, protecting it from oxidative stress.
• Anti-pollution shield: significantly reduces damage caused by fine particles (PM10) and other urban pollutants.
  • Radiance & evenness effect:
   – Asian skin: 86% of volunteers observed a brighter complexion after 56
  days.
   – Caucasian skin: significant improvement in luminosity and skin tone
  evenness after 28 days.
  • Prevents hyperpigmentation: helps reduce the appearance of dark spots while respecting the skin’s natural pigmentation process.

Function within SKINALYS® Formulations

A detoxifying and anti-pollution active, Detoxophane® protects the skin from environmental stressors, boosts its self-defense mechanisms, and reveals a brighter, more even, and luminous complexion.

Clinically Proven Skin Benefits (in vivo, in vitro & ex vivo)

• Urban shield: reduces fine particle (PM2.5) adhesion on the skin surface
  by up to −83%.
• Purifying effect: promotes the elimination of accumulated pollutants,
  for visibly clearer skin (+82% removal of PM2.5 particles).
• Antioxidant defense: neutralizes free radicals and heavy metals,
  reducing their harmful effects.
• Brighter complexion: after only 7 days, volunteers living in urban environments reported a clearer, more even, and more luminous complexion (consumer tests).
  • Anti-aging prevention: preserves skin elasticity and helps prevent pollution-induced dullness and dark spots.

Function within SKINALYS® Formulations

As an urban anti-pollution active, Exo-P™ acts like a second skin — blocking fine particles, detoxifying the surface, and protecting skin cells from environmental stressors for a healthier, more radiant, and resilient complexion.

Clinically Proven Skin Benefits (in vitro & in vivo)

• Deep hydration: on irritated skin, increases barrier hydration by up to +55% and reduces water loss by −53%, enabling faster recovery after irritation or stress.
• Strengthened barrier function: restores skin suppleness and elasticity while reducing dryness caused by environmental aggressions.
• Immediate soothing: reduces redness, itching, and discomfort, improving up to 80% of symptoms in sensitive or irritated skin.
• Accelerated repair: promotes healing, stimulates cell proliferation, and improves the appearance of marks and minor scars.

Function within SKINALYS® Formulations

An essential active for deep hydration, immediate soothing, and accelerated regeneration of sensitive skin — while reinforcing its natural protective barrier for
lasting comfort and resilience.